Correction to: Scientific Reports https://doi.org/10.1038/s41598-025-08646-3, published online 01 July 2025
The original version of this Article contained an error in Figure 5K, where the western blot images for ‘FN1’ and ‘β-actin’ were interchanged. The original Figure 5 and accompanying legend appear below.
Changes in FN1 expression and metastasis properties via miR-27b regulation in HNSC cell lines. Cell motility analyzed by (A) invasion and (B) wound healing assay in HSC3 and HSC3-M3 cell lines. (C) Cell proliferation and the relative expression of (D) miR-27b-3p, (E) FN1 mRNA and (F) FN1 protein in HSC3 and HSC3-M3 cell lines. The cells were transfected with miR-27b-3p inhibitor (HSC3) and mimic (HSC3-M3). The invasion (G, HSC3 and HSC3-M3) and wound healing (H, HSC3 and HSC3-M3) assays of cells after transfection showing the effect of miR-27b-3p on migration and invasion of the HNSC cell lines. Quantification results of invasion assay are additionally presented as bar graphs showing the relative invasion compared to the negative control group. The expression of (I, HSC3 and HSC3-M3) miR-27b-3p, (J, HSC3 and HSC3-M3) FN1 mRNA and (K, HSC3 and HSC3-M3) FN1 protein were shown to be related to the transfected with negative control sequence group, based on miR-27b-3p expression level regulation. The protein band intensity scanned and statistically analyzed by ImageJ. The relative expression of miRNA and mRNA were measured by RT-qPCR and the protein expression levels were analyzed by Western blot. Data are presented as the mean ± SEM of at least three independent experiments (N.S; non-significant).
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Cho, S.H., Kim, M., Kim, J. et al. Correction: miRNA centered regulatory networks identify FN1 and miR27b as metastatic drivers in HPV negative head and neck cancer. Sci Rep 15, 29512 (2025). https://doi.org/10.1038/s41598-025-14938-5
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DOI: https://doi.org/10.1038/s41598-025-14938-5
