Table 2 Multivariate analysis of clinicopathologic factors of overall survival.

From: Textbook outcome of gastric cancer surgery and lymph node evaluation as its parameter to improve long-term survival

 

All stage

Stage I

Stage II/III

HR

95% CI

P value

HR

95% CI

P value

HR

95% CI

P value

TO

NonTO

Reference

Reference

Reference

 

TO

0.63

0.49–0.81

< 0.001

0.52

0.33–0.84

0.007

0.69

0.51–0.93

0.01

Age

> 70

Reference

Reference

Reference

 

≤ 70

0.38

0.30–0.48

< 0.001

0.17

0.11–0.26

< 0.001

0.55

0.41–0.75

< 0.001

Sex

Male

Reference

Reference

Reference

 

Female

0.90

0.69–1.16

0.40

0.50

0.30–0.85

0.01

1.09

0.81–1.46

0.59

LND

D0

0.67

0.09–4.85

0.69

   

1.21

0.16–8.99

0.86

 

D1

3.07

0.70–13.53

0.14

   

4.97

1.04–23.63

0.04

 

D1+

Reference

Reference

Reference

 

D2

1.28

0.95–1.74

0.11

1.18

0.68–2.05

0.57

1.41

0.96–2.07

0.08

pT

T1

Reference

Reference

Reference

 

T2

1.61

1.01–2.55

0.05

1.82

1.00–3.31

0.05

1.07

0.42–2.74

0.89

 

T3

1.78

1.11–2.88

0.02

   

1.30

0.56–2.99

0.54

 

T4

5.16

3.31–8.04

< 0.001

   

3.70

1.76–8.26

0.001

pN

N0

Reference

Reference

Reference

 

N1

0.92

0.57–1.48

0.72

1.55

0.72–3.36

0.27

0.75

0.39–1.44

0.39

 

N2

1.66

1.11–2.49

0.02

   

1.53

0.93–2.51

0.09

 

N3

3.11

2.10–4.61

< 0.001

   

2.79

1.76–4.41

< 0.001

Retrieved lymph nodes

< 15

1.56

0.36–6.74

0.55

2.83

0.63–12.68

0.17

   

15–29

Reference

Reference

Reference

30–44

0.56

0.39–0.82

0.002

0.62

0.37–1.06

0.08

0.48

0.29–0.82

0.007

45–59

0.56

0.38–0.83

0.004

0.72

0.38–1.36

0.31

0.48

0.28–0.82

0.008

≥ 60

0.45

0.29–0.71

< 0.001

0.49

0.20–1.22

0.13

0.40

0.22–0.71

0.002

Size

 

1.07

1.02–1.11

0.003

1.07

0.95–1.20

0.25

1.07

1.02–1.12

0.006

  1. TO: textbook outcome, Ref: reference, LND: lymph node dissection, pT: pathological T stage, pN: pathological N stage
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