Fig. 1

Timeline of events in the ICU of our hospital during the year 2020. KPC-Kp (susceptible and resistant to ceftazidime-avibactam) recovered from patient between January and December are represented horizontally. KPC-Kp (resistant to ceftazidime-avibactam) recovered from environmental samples collected between July and September are represented in vertical (green zone). Length of stay (LOS) and LOS at the ICU of patients are indicated with a blue line and a dotted blue line, respectively. The ICU room where the patients stayed and where the environmental samples were collected is indicated by the framed number (on the left and below, respectively). Time of treatment with ceftazidime-avibactam (dose 2/0.5 g /8 h iv) is represented with a pink bar. The type of clinical sample from which KPC-Kp was isolated is represented by colored symbols (rectal, green hexagon; urine, yellow triangle; blood, red square; bronchial aspirate, blue cross; and catheter, purple circle). Patients involved in the KPC-62-Kp outbreak are framed in the red box.