Table 1 Main characteristics of the eligible studies included in this meta-analysis.
From: Impact of tumor necrosis factor-alpha gene variant in pediatric nephrotic syndrome: a meta-analysis
SNP | First author | Year | Ethnicity | Gender | Mean age | Genotyping method | Sample size | HWE P-value | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Case (M/F) | Control (M/F) | Case | Control | Case | Control | ||||||
TNFα 308 G/A (rs1800629) | Simin Sadeghi-Bojd | 2021 | Iran | 96 / 72 | 74 / 79 | 5.77 ± 3.01 | 6.03 ± 2.3 | PCR-RFLP | 168 | 153 | 0.36 |
DoaaM. Youssef | 2017 | Egypt | 76/74 | 71/79 | 4.4 ± 1.8 | 4.7 ± 1.9 | PCR-RFLP | 150 | 150 | 0.90 | |
Tabrez Jafar | 2011 | India | 106/44 | 399/170 | 11.0 ± 6.6 | 12.0 ± 3.5 | PCR-RFLP | 150 | 569 | 0.81 | |
Dina Abdel Razek Midan | 2017 | Egypt | 63/37 | 19/11 | 7.51 ± 3.12 | 8.47 ± 3.80 | PCR-RFLP | 100 | 30 | 0.62 | |
Hanan A. Madani | 2014 | Egypt | 31/29 | 20/10 | 6.19 | 6.44 | PCR-RFLP | 60 | 30 | 0.06 | |
