Table 4 Covariance analysis of the lipid-lowering effect of atorvastatin in three groups.
Changes in blood lipids | Genotype | Additive model | Dominant model | Recessive model | |||||
|---|---|---|---|---|---|---|---|---|---|
GG | GT | TT | F | P | F | P | F | P | |
ΔHDL-C | 0.088 ± 0.150 | 0.083 ± 0.226 | 0.031 ± 0.239 | 1.533 | 0.185 | 2.226 | 0.089 | 0.333 | 0.801 |
ΔLDL-C | -0.996 ± 0.696 | -0.540 ± 0.864 | -0.598 ± 0.561 | 4.198 | 0.001 | 2.179 | 0.094 | 5.142 | 0.002 |
ΔHDL-C/HDL-C | 0.096 ± 0.150 | 0.095 ± 0.209 | 0.046 ± 0.184 | 1.121 | 0.353 | 1.680 | 0.175 | 0.290 | 0.833 |
ΔLDL-C/LDL-C | -0.312 ± 0.195 | -0.179 ± 0.284 | -0.204 ± 0.232 | 3.042 | 0.013 | 1.708 | 0.169 | 3.539 | 0.017 |
Δ(LDL-C/HDL-C) | -1.146 ± 0.827 | -0.732 ± 0.847 | -0.615 ± 0.806 | 3.870 | 0.003 | 3.571 | 0.016 | 5.938 | 0.001 |
Δ(LDL-C/HDL-C)/(LDL-C/HDL-C) | -0.361 ± 0.204 | -0.239 ± 0.245 | -0.198 ± 0.354 | 2.551 | 0.031 | 2.156 | 0.097 | 4.312 | 0.006 |
