Fig. 5

(A) Circos plot illustrating significant differences in inter-regional FC among colorectal cancer survivors (n = 18) and healthy controls (n = 17) in regions associated with verbal memory (corrected p < 0.05). Brain region names and their corresponding lobes are annotated as such: FRN (frontal lobe, yellow), TL (temporal lobe, green), and PPC (posterior parietal cortex, purple). The color bar represents t-statistic values. (B) Axial view showing brain regions with significant differences between groups, primarily in the left temporal gyrus and the lateral and medial superior frontal gyrus. (C) Sagittal view of the medial left hemisphere showing brain regions with significant between-group differences including connections between the left middle temporal gyrus (MTG) and left superior frontal gyrus (SFG), as well as the left MTG and left medial SFG. These figures were generated using BrainNet Viewer 1.7 [https://www.nitrc.org/projects/bnv]³⁶. The full anatomical labels are listed in the Methods section “Inter-Regional Functional Connectivity Analysis”