Table 1 Demographic and clinical characteristics of the preterm infants that completed the study.
healthy infants (n = 108) | IVH infants (n = 26) | PVL infants (n = 16) | P-value | |
|---|---|---|---|---|
Neonatal characteristics | ||||
GA at birth, (weeks, median) | 29.50 (28.33, 30.57) | 28.93 (26.82, 31.14) | 29.14 (28.46, 30.25) | 0.471 |
Birth weight, (g, mean ± SD) | 1158.15 ± 241.57 | 1214.23 ± 365.90 | 1358.44 ± 363.23 | 0.028 |
Male, n (%) | 65 (60.2) | 15 (57.7) | 10 (62.5) | 0.951 |
SGA, n (%) | 17 (15.7) | 1 (3.8) | 2 (12.5) | 0.358 |
Singleton births, n (%) | 80 (74.1) | 14 (53.8) | 8 (50.0) | 0.037 |
5 min Apgar score, (median) | 9.0 (8.0, 9.0) | 9.0 (8.0, 10.0) | 9.0 (7.25, 9.0) | 0.411 |
Cesarean section births, n (%) | 83 (76.9) | 12 (46.2) | 15 (93.8) | 0.001 |
Maternal characteristics | ||||
Gestational diabetes*, n (%) | 24 (22.2) | 3 (11.5) | 3 (18.8%) | 0.058 |
Pregnancy hypertension, n (%) | 29 (26.9) | 6 (23.1) | 4 (25.0%) | 0.469 |
Fetal distress, n (%) | 36 (33.3) | 3 (11.5) | 3 (18.8%) | 0.052 |
Chorioamnionitis, n (%) | 11 (10.2) | 1 (3.8) | 1 (6.3%) | 0.718 |
PROM > 18 h, n (%) | 32 (29.6) | 8 (30.8) | 4 (25.0%) | 0.916 |
Amniotic fluid contamination, n (%) | 9 (12.2.0) | 5 (23.8) | 4 (21.1%) | 0.313 |
Treatment of premature infants | ||||
Duration of MV, (days, median) | 31.10 (23.73, 42.97) | 43.87 (16.99, 64.53) | 33.00 (26.66, 42.81) | 0.308 |
PMA at MRI scan, (weeks, median) | 36.22 (35.29, 37.71) | 37.00 (35.64, 38.21) | 35.57 (34.82, 37.15) | 0.116 |
Latest HCT at MRI, (mean ± SD) | 28.96 ± 3.92 | 32.17 ± 5.24 | 31.72 ± 5.89 | 0.001 |
Sepsis, n (%) | 15 (13.8) | 6 (23.1) | 1 (6.3%) | 0.333 |
NEC stage ≥ 2, n (%) | 15 (13.9) | 7 (26.9) | 3 (18.8%) | 0.249 |
BPD, n (%) | 26 (24.1) | 12 (46.2) | 4 (25.0%) | 0.076 |
hs-PDA, n (%) | 16 (14.8) | 11 (42.3) | 5 (31.3%) | 0.005 |
