Table 1 Univariate analysis of demographic characteristics and diagnostic & treatment factors affecting tuberculosis treatment failure.
Characteristics | Level | N | Treatment failure rate (95% CI) (%) | RR(95% CI) | P value |
|---|---|---|---|---|---|
Age (n = 33266) | < 25 | 5076 | 3.1 (2.6,3.6) | Baseline | – |
|  | 25–49 | 12,760 | 4.5 (4.1,4.9) | 1.4 (1.2, 1.7) | 0.000 |
| Â | 50+ | 15,430 | 9.4 (8.9,9.9) | 3.2 (2.7, 3.8) | 0.000 |
Sex (n = 33266) | Female | 11,349 | 4.2 (3.8,4.6) | Baseline | – |
| Â | Male | 21,917 | 7.8 (7.4,8.2) | 2.0 (1.8,2.2) | 0.000 |
Occupation(n = 32337) | Workers | 3681 | 4.9 (4.2,5.6) | Baseline | 0.000 |
| Â | Farmers/migrant workers | 15,252 | 8.5 (8.1,8.9) | 1.8 (1.5,2.1) | 0.000 |
| Â | Clerks/service industry | 5838 | 4.1 (3.6,4.6) | 0.8 (0.7,1.0) | 0.068 |
| Â | Healthcare workers/teachers/students | 2170 | 2.9 (2.2,3.6) | 0.6 (0.4,0.8) | 0.000 |
| Â | Retiree/unemployed person | 5396 | 6.9 (6.2,7.6) | 1.5 (1.2,1.8) | 0.000 |
Registered residence(n = 33265) | Local city | 24,851 | 7.1 (6.8,7.4) | Baseline | – |
| Â | Other city | 8414 | 4.8 (4.3,5.3) | 0.7 (0.6,0.7) | 0.000 |
Source of cases(n = 33191) | Self-initiated consultation | 17,667 | 6.2 (5.8,6.6) | Baseline | – |
| Â | Active screening | 1851 | 4.4 (3.5,5.3) | 0.7 (0.6,0.9) | 0.002 |
| Â | Recommended referral | 13,673 | 7.4 (7,7.8) | 1.2 (1.1,1.3) | 0.000 |
Time delayed in treatment (n = 33227) | ≤ 30 days | 24,538 | 6 (5.7,6.3) | Baseline | – |
|  | > 30 days | 8689 | 8.1 (7.5,8.7) | 1.4 (1.3,1.5) | 0.000 |
Diagnosis classification(n = 33266) | Other* | 4771 | 0.3 (0.1,0.5) | Baseline | – |
| Â | Hematogenous dissemination | 153 | 8.5 (4.1,12.9) | 31.6 (14.6,68.4) | 0.000 |
| Â | Secondary | 28,342 | 7.6 (7.3,7.9) | 27.9 (16.5,47.3) | 0.000 |
Etiology(n = 33266) | Negative | 19,874 | 1.3 (1.1,1.5) | Baseline | – |
| Â | Positive | 13,392 | 14.4 (13.8,15) | 12.7 (11.1,14.5) | 0.000 |
Comorbidity(n = 29734) | None | 27,128 | 5.5 (5.2,5.8) | Baseline | – |
| Â | Pneumoconiosis | 36 | 13.9 (2.6,25.2) | 2.8 (1.1,7.1) | 0.035 |
| Â | Diabetes/chronic disease | 2570 | 13 (11.7,14.3) | 2.6 (2.3,2.9) | 0.000 |
Registration classification(n = 33266) | New case | 30,621 | 5.5 (5.2,5.8) | Baseline | – |
| Â | Initial treatment failure | 560 | 22.5 (19,26) | 4.9 (4.0,6.1) | 0.000 |
| Â | Relapse | 2085 | 17.1 (15.5,18.7) | 3.5 (3.1,4.0) | 0.000 |
Use of FDC(n = 33252) | Yes | 2639 | 8.5 (7.4,9.6) | Baseline | – |
| Â | No | 30,613 | 3.1 (2.6,3.6) | 0.7 (0.6,0.8) | 0.000 |
