Table 1 Co-localization analysis results of eight genes and LUSC.

From: Druggable genome-wide Mendelian randomization integrating GWAS and eQTL/pQTL data identifies targets for lung squamous cell carcinoma

Gene

Dataset

Nsnp

PPH0

PPH1

PPH2

PPH3

PPH4

DNMT1

ieu_b_4953

3276

1.56E-139

0.6278391

4.55E-140

0.1835922

0.1885687

ACSS2

ieu_b_4954

2200

5.838E-23

0.7335337

1.755E-23

0.2204597

0.0460066

YBX1

ieu_b_4955

2861

0.545739

0.2037614

0.1467671

0.0547491

0.0489834

SELENOS

ieu_b_4956

3389

5.925E-45

0.6093853

2.446E-45

0.2514

0.1392147

PPARA

ieu_b_4957

4205

2.561E-11

0.5863268

1.336E-11

0.3056681

0.1080051

MST1

ieu_b_4953

1197

4.78E-298

0.7656058

6.17E-299

0.0986691

0.1357251

CPA4

ieu_b_4953

807

1.83E-297

0.6933091

4.47E-298

0.1693557

0.1373352

MPO

ieu_b_4953

523

5.845E-38

0.7291001

1.332E-38

0.1660102

0.1048896

DNMT1

finngen

6309

1.53E-139

0.6182436

8.73E-140

0.3522002

0.0295562

ACSS2

finngen

4096

4.789E-23

0.6017897

1.656E-23

0.2078548

0.1903555

YBX1

finngen

4800

0.2987978

0.1343479

0.3573422

0.1606222

0.0488898

SELENOS

finngen

6636

5.029E-45

0.5171751

3.406E-45

0.3501935

0.1326314

PPARA

finngen

7782

2.173E-11

0.5853339

1.457E-11

0.3923886

0.0222775

MST1

finngen

1817

4.93E-298

0.8617023

5.33E-299

0.0929885

0.0453092

CPA4

finngen

1098

1.98E-297

0.7821006

3.45E-298

0.1360754

0.081824

MPO

finngen

643

8.706E-46

0.9079695

4.043E-47

0.0421208

0.0499097

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