Table 2 SMR analysis and HEIDI test for eight MR-identified genes.

From: Druggable genome-wide Mendelian randomization integrating GWAS and eQTL/pQTL data identifies targets for lung squamous cell carcinoma

Dataset

Gene

p_SMR

p_HEIDI

ieu_b_4953

DNMT1

0.03000431

0.09929643

SELENOS

0.03925309

0.06218809

ACSS2

0.02926428

0.06428013

YBX1

0.025176039

0.9685611

PPARA

0.03250315

0.6433497

MST1

0.03289406

0.9998272

CPA4

0.03312131

0.8153408

MPO

0.01468984

0.65253

finngen

DNMT1

0.03122919

0.2046011

SELENOS

0.03240613

0.419712

ACSS2

0.01713829

0.6835821

YBX1

0.02445203

0.2962605

PPARA

0.02457122

0.2844321

MST1

0.02636548

0.2080907

CPA4

0.01072964

0.2387459

MPO

0.02436019

0.4643567