Table 1 Clinical features of ε4 carriers and non-ε4 carriers.
Non-ε4 carriers (ε2/ε3 or ε3/ε3) (n = 83) | ε4 carriers (ε3/ε4 or ε4/ε4) (n = 18) | P | |
|---|---|---|---|
Gender(male) (No.) (%) | 51(61.45%) | 16(88.89%) | 0.026 |
Age (mean ± SD) (yr) | 62.75 ± 11.65 | 62.67 ± 11.02 | 0.979 |
History of stroke/TIA (No.) (%) | 24(28.92%) | 7(38.89%) | 0.406 |
History of cerebral hemorrhage (No.) (%) | 1(1.20%) | 1(5.56%) | 0.326 |
Hypertension (No.) (%) | 52(62.65%) | 13(72.22%) | 0.442 |
Diabetes (No.) (%) | 23(27.71%) | 6(33.33%) | 0.633 |
Hyperlipidemia (No.) (%) | 0 | 1(5.56%) | 0.178 |
Coronary heart disease (No.) (%) | 13(15.66%) | 5(27.78%) | 0.380 |
Atrial fibrillation (No.) (%) | 13(15.66%) | 1(5.56%) | 0.454 |
Smoking (No.) (%) | 27(32.53%) | 4(22.22%) | 0.390 |
Drinking (No.) (%) | 8(9.64%) | 0 | 0.373 |
BMI (mean ± SD) | 23.95 ± 3.02 | 24.61 ± 2.21 | 0.387 |
HbA1c (median) (IQR) (%) | 6(5.7, 6.7) | 6.65(5.8, 8) | 0.134 |
TC (mean ± SD) (mmol/l) | 4 ± 1.08 | 4.11 ± 1.14 | 0.717 |
TG (median) (IQR) (mmol/l) | 1.22(0.96, 1.71) | 1.17(0.89, 1.71) | 0.776 |
HDL-C (mean ± SD) (mmol/l) | 1.03 ± 0.28 | 0.99 ± 0.26 | 0.570 |
LDL-C (mean ± SD) (mmol/l) | 2.31 ± 0.71 | 3.05 ± 0.68 | <0.001 |
HCY (median) (IQR) (umol/L) | 16.1(11.4, 25) | 16(12.38, 21.03) | 0.759 |
UA (median) (IQR) (umol/L) | 305.70(244, 362.54) | 269.5(243.57, 305.7) | 0.312 |
HGB (median) (IQR) (g/l) | 139(129, 146) | 137(130.25, 157.50 | 0.703 |
NIHSS (median) (IQR) | 5(3, 9) | 10.5(6.75, 16.75) | 0.004 |
The side of artery occlusion(right) (No.) (%) | 46(55.42%) | 12(66.67%) | 0.382 |
Occluded Vessel | 0.261 | ||
ICA | 13(15.66%) | 2(11.11%) | |
ICA and MCA simultaneously occluded | 11(13.25%) | 0(0%) | |
MCA | 59(71.08%) | 16(88.89%) | |
HIR ≥ 0.4 (No.) (%) | 11(13.25%) | 8(44.44%) | 0.006 |
HIR (median) (IQR) | 0.15(0.04, 0.33) | 0.35(0.17, 0.56%) | 0.012 |
IC volume (median) (IQR) (ml) | 38(20.3, 70.9) | 87.85(50.38, 114.35) | 0.003 |
Ischemic penumbra volume (mean ± SD) (ml) | 133.27 ± 70.40 | 153.21 ± 96.54 | 0.312 |
