Fig. 6
From: Metformin lotion as a novel approach to prevent tendinopathy induced by mechanical overuse
Met lotion reduces ITR-induced collagen II formation. ML application decreases collagen II expression (d–i), which was elevated by ITR (a–c). Semi-quantitative analysis shows a 1.8-fold and 2.9-fold decrease in collagen II with 3% and 6% ML application, respectively (j). b,e,h: Enlarged green box areas from images a,d,g. c,f,i: Enlarged yellow box areas from images b,e,h. j: Semi-quantitative results from 45 images (15 sections from 5 mice per group) are presented as mean ± SD (n = 5). ML: Met Lotion. Scale bars: 500 μm (white); 200 μm (yellow); 50 μm (green).
