Fig. 8
From: Metformin lotion as a novel approach to prevent tendinopathy induced by mechanical overuse
Met lotion decreases TGF-β1 expression in tendons. ML application significantly decreases TGF-β1 expression in ITR tendons in a concentration-dependent manner, with a 7.2-fold and 23.3-fold reduction for 3% and 6% ML application, respectively (e–l,m), compared to ITR tendons (a–d,m). m: Semi-quantitative results from 45 images (15 sections from 5 mice per group) are presented as mean ± SD (n = 5). ML: Met Lotion. Scale bars: 500 μm (white); 200 μm (yellow); 100 μm (green); 50 μm (orange).
