Fig. 1 | Scientific Reports

Fig. 1

From: Identification of SUMOylation modifiers involved in lung adenocarcinoma progression and Osimertinib resistance by integrated bioinformatics analysis

Fig. 1

Screening differentially expressed gene signature associated with small ubiquitin-related modifier in LUAD. (A) Volcano plots of the gene expression signature analysis in LUAD Case based on TCGA-LUAD. (B) Heat map of differential genes in LUAD Case. (C) Volcano plots of the gene expression signature analysis in GSE200893. (D) Heat map of differential genes in GSE200893. (E) Venn diagram of intersection genes. X-axis: number of intersection genes. Y-axis: number of differentially expressed genes in DEGs_LUAD, DEGs_Tolerant, and SRGs. (F) The results of enrichment analysis, the TOP10 functional items of each part (significance ranking) were displayed, the box size indicates the number of enriched genes. (G) The results of enriched KEGG pathways, the TOP5 functional pathway (significance ranking) and its genes were displayed, circle size indicates the number of enriched genes.

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