Fig. 2
From: Horse model of spontaneous atrial fibrillation share proteomic changes with humans
Pathway analysis of proteins identified in left atrium from horses with atrial fibrillation. (A) Principal component analysis (PCA) plot of log2-transformed intensities associated with healthy control (CTR) and atrial fibrillation (AF) horse samples. Components 1 and 2 are presented. AF = red, CTR = blue. (B) Volcano plot comparing protein abundance in left atrium (LA) regions from AF horses. Log2 fold change (logFC) difference and non-adjusted p-value are presented in volcano plot. Red = upregulated and blue = downregulated in AF compared to CTR. (C and D) Significance score identified in enrichment analysis of upregulated or downregulated proteins using different databases; GO Biological Process (beige), GO Cellular Component (grey), and GO Molecular Function (blue).
