Fig. 8

Identification of atrial fibrillation induced left atrial protein changes between humans and horses Diagrams showing number of significantly regulated proteins that are shared with two previous studies identifying atrial fibrillation (AF) expression profiles in left atria from humans on either proteomic (A)²⁰ or transcriptomic level (B)²². (C and D) Scatter plot comparing fold change (logFC) differences of shared significantly regulated AF proteins from our study and a previous studies Red = upregulated, blue = downregulated in AF compared to control (CTR). (E and F), significance score (-log10 transformed false-discovery rate (FDR)) identified in enrichment analysis of shared AF proteins using different databases; GO Biological Process (grey), GO Cellular Component (blue), KEGG (purple)⁵⁹, Reactome (red).