Table 2 Demographics and clinicopathological characteristics of patients with esophageal carcinoma.

Characteristics	All patients (n = 1542)		Training cohort (N = 1116)		Validation cohort (N = 426)		P value
Characteristics	Number	%	Number	%	Number	%	P value
Sex
Male	1288	83.5	931	83.4	357	83.8	0.857
Female	254	16.5	185	16.6	69	16.2	0.857
Race
White	1274	82.6	923	82.7	351	82.4	0.885
Unwhite	268	17.4	193	17.3	75	17.6	0.885
Age
< 65 years	877	56.9	630	56.5	247	58.0	0.588
≥ 65 years	665	43.1	486	43.5	179	42.0	0.588
Marriage
Married	861	55.8	627	56.2	234	54.9	0.658
Unmarried	681	44.2	489	43.8	192	45.1	0.658
Chemotherapy
None	478	31.0	351	31.5	127	29.8	0.534
Yes	1064	69.0	765	68.5	299	70.2	0.534
Radiotherapy
None	771	50	561	50.3	210	49.3	0.733
Yes	771	50	555	49.7	216	50.7	0.733
Histology
Adenocarcinoma	1032	66.9	751	67.3	281	66.0	0.619
Non- adenocarcinoma	510	33.1	365	32.7	145	34.0	0.619
Primary site
Cervical/Upper	61	4.0	40	3.6	21	4.9	0.058
Thoracic/middle	279	18.1	201	18.0	78	18.3
Abdominal/lower	1119	72.6	805	72.1	314	73.7
Overlapping	83	5.4	70	6.3	13	3.1
Surgery
None	1459	94.6	1054	94.4	405	95.1	0.626
Yes	83	5.4	62	5.6	21	4.9	0.626
Grade
I + II	552	35.8	401	35.9	151	35.4	0.859
III + IV	990	64.2	715	64.1	275	64.6	0.859
T Stage
T1	414	26.8	295	26.4	119	27.9	0.620
T2	84	5.4	66	5.9	18	4.2
T3	390	25.3	285	25.5	105	24.6
T4	399	25.9	291	26.1	108	25.4
Tx	255	16.5	179	16.0	76	17.8
N Stage
N0	417	27.0	299	26.8	118	27.7	0.684
N1	998	64.7	721	64.6	277	65.0
Nx	127	8.2	96	8.6	31	7.3
M Stage
M1a	74	4.8	51	4.6	23	5.4	0.496
M1b	1468	95.2	1065	95.4	403	94.6	0.496
Vital status
Alive	34	2.2	24	2.2	10	2.3	0.814
Death	1508	97.8	1092	97.8	416	97.7	0.814

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