Fig. 6 | Scientific Reports

Fig. 6

From: Single-cell transcriptome sequencing reveals tumor stem cells and their molecular characteristics in intrahepatic cholangiocarcinoma

Fig. 6

Cellular communication between tumor clusters. (A) The network centrality scores are displayed in a heatmap, showing the top 19 incoming (left) and outgoing (right) signals across 10 cell clusters. (B) A scatter plot shows the division of 19 signaling pathways into four groups. (C–E) Figures show the network centrality scores (heatmap), ligand-receptor pairs (bar chart), and gene expression of receptor-ligand pairs (violin plots) for the top three signaling pathways. (F and G) River plots display the communication patterns coordinating secretory cell clusters with outgoing signaling pathways and target cell clusters with incoming signaling pathways.

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