Table 2 Associations of temperature trajectories with in-hospital mortality in all patients with SA-AKI.

Variables	Model 1		Model 2		Model 3
Variables	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Class kind
M3	Ref		Ref		Ref
L1	3.37 (2.25–5.06)	< 0.001	2.43 (1.60–3.69)	< 0.001	2.41 (1.58–3.66)	< 0.001
L2	1.23 (0.93–1.62)	0.144	1.47 (1.11–1.96)	0.008	1.48 (1.11–1.97)	0.007
L3	0.96 (0.77–1.20)	0.710	1.27 (1.01–1.60)	0.042	1.27 (1.01–1.59)	0.043
L4	1.30 (1.09–1.55)	0.003	1.30 (1.08–1.55)	0.005	1.29 (1.08–1.54)	0.005
L5	1.38 (0.69–2.78)	0.360	0.78 (0.38–1.61)	0.505	0.78 (0.38–1.59)	0.488
M1	1.45 (1.19–1.76)	< 0.001	1.29 (1.06–1.57)	0.012	1.29 (1.06–1.57)	0.012
M2	0.86 (0.76–0.98)	0.023	1.04 (0.91–1.19)	0.541	1.05 (0.92–1.19)	0.495
M4	0.85 (0.66–1.09)	0.200	1.27 (0.99–1.64)	0.064	1.28 (0.99–1.66)	0.056
H1	0.86 (0.32–2.30)	0.764	0.71 (0.26–1.90)	0.494	0.72 (0.27–1.93)	0.512
H2	0.72 (0.51–1.02)	0.061	0.93 (0.66–1.32)	0.692	0.94 (0.67–1.34)	0.739
H3	0.75 (0.56-1.00)	0.053	0.81 (0.60–1.09)	0.158	0.81 (0.61–1.09)	0.171
H4	1.91 (0.91–4.03)	0.088	1.71 (0.80–3.64)	0.164	1.73 (0.81–3.68)	0.158
Temperature	0.87 (0.83–0.90)	< 0.001	0.89 (0.85–0.93)	< 0.001	0.89 (0.85–0.93)	< 0.001
Temperature
36–38	Ref		Ref		Ref
< 36	1.26 (1.11–1.42)	< 0.001	1.29 (1.14–1.48)	< 0.001	1.29 (1.13–1.47)	< 0.001
> 38	0.79 (0.64–0.98)	0.031	0.84 (0.68–1.04)	0.113	0.84 (0.68–1.05)	0.124

HR hazard ratio; CI confidence intervals; Ref reference. Model 1was crude model, Model 2 adjusting RRT, age, insurance, marital status, first care unit, severity KAI stage, urine output 24h, SOFA, CCI, weight, heart rate, respiratory rate, SPO2, RBC, hematocrit, RDW, eGFR, PT, BUN, lactate, and anion gap. Model 3 adjusting RRT, age, insurance, marital status, first care unit, severity KAI stage, urine output 24h, SOFA, CCI, weight, heart rate, respiratory rate, SPO2, RBC, hematocrit, RDW, eGFR, PT, BUN, lactate, anion gap, buprofen, aspirin, and acetaminophen.

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