Fig. 5 | Scientific Reports

Fig. 5

From: Antinuclear antibodies in early multiple sclerosis reflect systemic lupus erythematosus shared risk factors

Fig. 5

Forest plots of the multivariate Cox proportional hazards models for time to McDonald 2017 MS and CDMS diagnosis. In panel (A) time to McDonald 2017 MS is shown for the total population and panel (B) for the MS subgroup. In both analyses, no association is found with ANA positivity and earlier McDonald MS diagnosis (HR 0.98, 95% CI 0.60–1.60 and HR 1.20, 95% CI 0.71–1.90). In panel (C) time to CDMS is shown for the total population and in (D) the time to CDMS for the MS subgroup. In total population and MS subgroup, no association between ANA status and earlier CDMS diagnosis was found (HR 0.71, 95% CI 0.37–1.36 and HR 0.84, 95% CI 0.43–1.60).

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