Fig. 5 | Scientific Reports

Fig. 5

From: Human vaginal Lactobacillus Jensenii -derived (-)-Terpinen-4-ol restores antibiotic sensitivity by inhibiting efflux pumps in drug resistant E. coli and K. pneumoniae

Fig. 5

(-)-Terpinen-4-ol synergistically potentiates bactericidal effect of erythromycin in infected zebrafish. (A) Different treatment combinations (Erythromycin (Ery), (-)-Terpinen-4-ol (Ltr- Lactobacillus derived and Tr- Commercially procured) were administered 2–3 h post-infection. The colony counts were scored after 24 h and represented as log CFU/ml. Experiment was performed in triplicates and statistical analyses were performed using Student’s t-test. (p< ***0.0001) (B) Histopathology analysis of Muscle and Liver tissues at 40X maginification (N = 3).

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