Table 1 Baseline characteristics before propensity score matching.
Total (n = 1664) | Control (n = 1524) | GLP-1RA (n = 140) | P | |
---|---|---|---|---|
Age, years | 71.74 ± 11.25 | 72.70 ± 10.83 | 61.28 ± 10.39 | < .001 |
Male, n (%) | 1140 (68.51) | 1033 (67.78) | 107 (76.43) | 0.035 |
Hypertension, n (%) | 1291 (77.63) | 1183 (77.68) | 108 (77.14) | 0.885 |
Atrial fibrillation, n(%) | 126(7.5) | 119(7.81) | 7(5.19) | 0.233 |
Heart failue,n(%) | 221(13.28) | 182(11.94) | 16(11.43) | 0.551 |
Acute coronary syndrome,n(%) | 331(19.89) | 302(19.82) | 29(20.71) | 0.882 |
Diabetes duration, years | 16.43 ± 5.60 | 16.52 ± 5.40 | 15.45 ± 7.40 | 0.096 |
Smokers, n (%) | 741 (44.53) | 658 (43.18) | 83 (59.29) | < .001 |
BMI, kg/m2 | 24.89 ± 7.57 | 24.74 ± 7.75 | 26.44 ± 5.20 | 0.011 |
HbA1c baseline, % | 7.92 ± 1.59 | 7.84 ± 1.56 | 8.61 ± 1.67 | < .001 |
Fasting blood glucose, mmol/L | 7.97 ± 3.38 | 7.88 ± 3.29 | 8.91 ± 4.05 | < .001 |
Total cholesterol, mmol/L | 3.93 (3.24, 4.75) | 3.92 (3.22, 4.71) | 4.18 (3.43, 4.94) | 0.007 |
HDL cholesterol, mmol/L | 0.93 (0.78, 1.12) | 0.93 (0.78, 1.12) | 0.94 (0.79, 1.12) | 0.484 |
LDL cholesterol, mmol/L | 2.52 (1.89, 3.32) | 2.48 (1.88, 3.31) | 2.85 (2.15, 3.46) | 0.005 |
Triglycerides, mmol/L | 1.55 (1.14, 2.16) | 1.54 (1.13, 2.15) | 1.69 (1.23, 2.28) | 0.054 |
Creatinine, μmol/L | 78.00 (63.00, 99.00) | 79.00 (64.00, 100.00) | 72.00 (60.00, 88.00) | 0.005 |
cTroponin I, ng/ml | 0.01 (0.00, 0.18) | 0.01 (0.00, 0.12) | 0.04 (0.01, 1.64) | < .001 |
Beta-blockers, n (%) | 741 (44.53) | 671 (44.03) | 70 (50.00) | 0.174 |
ACEI/ARB/ARNI, n (%) | 938 (56.37) | 850 (55.77) | 88 (62.86) | 0.106 |
Metformin, n (%) | 1141 (68.57) | 1045 (68.57) | 96 (68.57) | 1.000 |
Thiazolidinediones, n (%) | 162 (9.74) | 146 (9.58) | 16 (11.43) | 0.480 |
Insulins, n (%) | 491 (29.51) | 443 (29.07) | 48 (34.29) | 0.195 |
SGLT2 inhititors, n (%) | 844 (50.72) | 769 (50.46) | 75 (53.57) | 0.481 |
Statins, n (%) | 1264 (75.96) | 1150 (75.46) | 114 (81.43) | 0.114 |
Antiplatelet drugs, n (%) | 1462 (87.76) | 1334(87.53) | 128 (91.43) | 0.139 |
Anticoagulant drugs, n (%) | 108 (6.49) | 96 (6.3) | 12 (8.57) | 0.081 |