Table 4 Combined statistical descriptors and significance testing of m/z and intensity parameters in tear samples from healthy subjects and choroidal melanoma patients.

From: Non-invasive detection of choroidal melanoma via tear-derived protein corona on gold nanoparticles: a machine learning approach

Parameter

Group

Mean ± SD

Median ± SD

Std ± SD

Skewness ± SD

Kurtosis ± SD

CV ± SD (%)

SNR ± SD

T-Statistic

P-Value

Significant

Cohen’s d

m/z

Healthy

424.16 ± 0.02

373.82 ± 0.19

277.88 ± 0.21

0.43 ± 0.003

-1.04 ± 0.01

65.51 ± 0.05

1.53 ± 0.001

1.85

0.082

No

0.63

Cancer

414.28 ± 22.68

363.95 ± 22.72

274.14 ± 8.56

0.44 ± 0.01

-1.04 ± 0.01

66.26 ± 1.73

1.51 ± 0.04

    

Intensity

Healthy

111.02 ± 10.30

63.89 ± 6.63

514.22 ± 48.63

70.47 ± 6.22

6665.91 ± 1092.15

464.97 ± 42.77

0.22 ± 0.02

4.78

0.00013

Yes

1.64

Cancer

56.41 ± 47.40

34.06 ± 28.05

241.28 ± 174.39

70.58 ± 13.09

6745.98 ± 2258.78

525.87 ± 170.73

0.21 ± 0.05

    
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