Table 1 Comparison of pleural effusions with ADA levels ≥ 25 IU/L.

From: Development and validation of a predictive model for tuberculous pleural effusion with high adenosine deaminase

Variable

TPE

n = 133

Non-TPE

n = 104

P-value

Sex

Male

83 (62.4)

77 (74.0)

0.058

Female

50 (37.6)

27 (26.0)

Age (years)

52 (27, 69)

68 (58, 77)

 < 0.001

Pleural effusion

 TP (g/L)

50.4 (46.7, 54.6)

43.5 (32.5, 50.8)

 < 0.001

 GLU (mmol/L)

5.5 (4.4, 6.4)

3.3 (0.2, 6.4)

 < 0.001

 LDH (IU/L)

411 (277, 649)

1478 (444, 2837)

 < 0.001

 ADA (IU/L)

46 (36, 54)

36 (30, 65)

0.054

 LDH/ADA

8.9 (6.7, 13.3)

43.9 (10.0, 62.4)

 < 0.001

 Nucleated cells (*106/L)

2490 (1330, 3880)

3300 (870, 8705)

0.135

 Lymphocytes (%)

85 (60, 90)

12 (5, 75)

 < 0.001

 Neutrophils (%)

10 (5, 15)

65 (10, 90)

 < 0.001

 Macrophages (%)

5 (5, 10)

8 (5, 15)

0.213

Serum

 TB (μmol/L)

10.8 (7.9, 14.1)

14.2 (9.0, 20.7)

 < 0.001

 TP (g/L)

67.2 (63.5, 71.8)

63.6 (58.1, 70.4)

 < 0.001

 ALB (g/L)

34.5 ± 3.9

30.7 ± 5.5

 < 0.001

 GLU (mmol/L)

5.5 (4.9, 6.8)

5.9 (5.2, 7.2)

0.089

 TC (mmol/L)

3.860 (3.370, 4.350)

3.480 (2.780, 4.370)

0.027

 LDH (IU/L)

177.0 (154.0, 201.0)

194.0 (161.0, 272.0)

0.002

 CEA (ng/mL)

1.2 (0.8, 2.0)

2.3 (1.3, 3.9)

 < 0.001

 Ca125 (IU/mL)

117.6 (65.9, 172.9)

56.8 (24.4, 144.3)

 < 0.001

Peripheral blood

 WBC (*109/L)

6.0 (4.9, 7.3)

9.4 (5.5, 13.9)

 < 0.001

 Neutrophil count (*109/L),

4.2 (3.2, 5.4)

7.5 (3.8, 11.3)

 < 0.001

 Lymphocyte count (*109/L)

1.0 (0.7, 1.3)

0.9 (0.6, 1.4)

0.156

 Monocyte count (*109/L)

0.6 (0.4, 0.7)

0.6 (0.4, 0.9)

0.240

 Platelet count (*109/L)

312 ± 88

270 ± 123

0.004

 NLR

4.0 (3.0, 5.6)

6.7 (4.1, 15.0)

 < 0.001

 PLR

295.1 (219.2, 396.6)

263.4 (176.7, 430.7)

0.424

 PNR

69.6 (51.6, 97.4)

40.3 (21.2, 58.4)

 < 0.001

 LMR

1.7 (1.3, 2.4)

1.5 (0.9, 2.4)

0.059

Plasma

 D-dimer (mg/L)

2.6 (1.6, 4.9)

2.1 (1.0, 3.3)

0.016

 APTT (s)

31.7 (29.7, 34.9)

30.6 (27.6, 34.2)

0.030

 FBG (g/L)

5.2 (4.3, 5.6)

4.8 (3.6, 5.8)

0.361

  1. Data are reported as the median (interquartile range), number (%), or average ± standard deviation.
  2. TP, Total protein; GLU, Glucose; LDH, Lactate dehydrogenase; ADA, Adenosine deaminase; TB, Total bilirubin; ALB, Albumin; TC, Total cholesterol; CEA, Carcinoembryonic antigen; Ca125, Carbohydrate antigen 125; WBC, White blood cells; NLR, Neutrophil to lymphocyte ratio; PLR, Platelet to lymphocyte ratio; PNR, Platelet to neutrophil ratio,; LMR, Lymphocyte to monocyte ratio; APTT, Activated partial thromboplastin time; FBG, Fibrinogen.
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