Fig. 4 | Scientific Reports

Fig. 4

From: The administration of passive and active immunotherapy against Syntenin-1 decreased the tumoral growth and pulmonary metastasis in a murine model of triple-negative breast cancer

Fig. 4

The effect of active and passive treatment with the KA-11-MAP8 peptide and polyclonal antibody on tumor growth and lung metastasis in Balb/c mice. (A) Representative images of breast tissue and lungs from the control and experimental groups. (B) Volume of the primary tumor, with comparisons made between Group 3 and the other groups. The statistical significance is noted as follows: *p = 0.0104 (Group 4), **p = 0.0082 (Group 5), and ***p = 0.0077 (Group 6). (C) Tumor weight measurements. (D) Weight of the lungs, expressed in grams. Groups 1 to 7 (G1-G7) are indicated. The plus sign (+) in the passive treatment denotes the dose of polyclonal antibody administered: + : 1 mg/kg; ++: 3 mg/kg; +++: 5 mg/kg.

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