Fig. 6

Detection of antibody isotypes and sub-isotypes in serum collected from both control and experimental groups. The measured antibody levels include total IgG (heavy + light chains), IgM, and specific IgG sub-isotypes: IgG1, IgG2a, IgG2b, and IgG3. Groups 1 to 7 are labeled as G1 through G7. In the passive treatment section, the '+' symbol indicates the dose of the administered polyclonal antibody: + indicates 1 mg/kg, ++ indicates 3 mg/kg, and +++ indicates 5 mg/kg.