Fig. 3

Representative components for the three compartments superimposed to the post-contrast images are shown in Panel a (CNA: Complete Necrotic Area, top row; PNA: Partial Necrotic Area, middle row; VTA: Viable Tumor Area, bottom row). Panel b shows the averaged temporal profile of signal enhancement compared to baseline signal (t=-1). The time point of contrast-agent injection is marked by a dashed vertical line at t = 0; the shaded area is obtained with the stretched-exponential model (SEM). Data are expressed as mean ± standard deviation.