Fig. 7
Representative histological slice of a control tumor stained with anti-CD31 antibody. CD31 + blood vessels (brown) are homogeneously distributed throughout both central and peripheral regions, without the formation of a vascularized rim as seen in treated mice: Panel A and Panel B show panoramic views of the tumor, encompassing both central and peripheral regions, where CD31 + vessels are uniformly distributed. Panel C and Panel D illustrate higher-magnification views of the central tumor area, confirming consistent vascular density across the tissue. Panel E presents a detailed close-up from the peripheral zone, further demonstrating the absence of any localized vascular rim.
