Table 5 Docking score of the designed Benzimidazole Derivatives.

From: Molecular docking and pharmacokinetics of benzimidazole-based FtsZ inhibitors for tuberculosis

Comp. Code	R	Docking score (kcal/mol)
P1	CH₂CH₃	− 8.2
P2	CH₂CH₂CH₂CH₃	− 6.9
P3	CH₂CH₂CH₃	− 6.8
P4	CH₂COOH	− 8.5
P5	2–OHC₆H₄	− 8.2
P6	CH₂CH₂COOH	− 7.3
P7	3–OHC₆H₄	− 7.4
P8	4–OHC₆H₄	− 8.0
P9	2,3–OHC₆H₃	− 9.4
P10	2,4–OHC₆H₃	− 7.9
P11	2,5–OHC₆H₃	− 8.6
P12	2,6–OHC₆H₃	− 9.0
P13	3,4–OHC₆H₃	− 8.1
P14	3,5–OHC₆H₃	− 8.8
P15	3–ClC₆H₄	− 7.8
P16	2–CH₃C₆H₄	− 8.4
P17	2–COOHC₆H₄	− 7.4
P18	2–NH₂C₆H₄	− 7.9
P19	3–NO₂C₆H₄	− 8.3
P20	2–COOHC₆H₄	− 9.0
P21	3–BrC₆H₄	− 8.0
P22	4–BrC₆H₄	− 8.3
P23	4–CH₂BrC₆H₄	− 8.1
P24	4–NO₂C₆H₄	− 8.2
P25	3,4,5–OHC₆H₂	− 7.8
P26	CH=CH–C₆H₅	− 7.5
P27	6–NO₂C₆H₄	− 8.6
P28	4–CH₃C₆H₄	− 8.1
P29	2–NH₂–3–OH–C₆H₃	− 7.2
P30	CH=CH–3,4,5–OHC₆H₃	− 8.6
P31	CH=CH–4–OHC₆H₄	− 7.7
P32	2–OCOCH₃C₆H₄	− 9.6
P33	2–OH–3–CH₃C₆H₃	− 7.8
P34	2–OH–5–SO₃HC₆H₃	− 8.6
P35	3–CH₃–4–NO₂C₆H₃	− 7.8
P36	4–CH₃–6–NO₂C₆H₃	− 7.8
P37	CH₃CHOH	− 7.9
P38	2,5–OHC₆H₃	− 8.9
P39	3–OCH₃–4–OHC₆H₃	− 7.8
P40	4–OCH₃C₆H₄	− 8.3
P41	COCH₃	− 7.4
P42	CH₂–CHOH–COOH	− 7.7
P43	Pyridine	− 7.6
P44	CH=CH–COOH	− 8.1
P45	CH=CH₂	− 7.6
P46	(CH₂OH)₅	− 8.3
P47	COOH	− 7.1
P48	(CH₂)₃COOH	− 7.9
P49	(CH₂OH)₂COOH	− 8.3
P50	CH₂NHCOC₆H₅	− 9.0
PAS	–	− 4.7
Isoniazid	–	− 5.5

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