Fig. 7
Reagents and conditions: (a) Appropriate acid, EDCI, HOBt, TEA, rt, 16 h; (b) BBr3, DCM, room temperature, 4 h; (c) Bergaptol, Ph3P, DIAD, THF, 0 °C to r.t, 16 h. Numbers in brackets denote; (6) piperidine derivative, (7c&e) corresponding amides, (11) 5-methoxypsoralen (Bergapten), (12) Bergaptol, (13a, b) target hybrid analogs.
