Fig. 4
From: AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype
AMIGO2 silencing suppresses tumorigenesis in vivo in MKN45 and DLD-1 cells Different numbers of MNN45 cells (a–c) and DLD-1 cells (d–f) and their transfectants were injected subcutaneously into non-obese diabetic/severe combined immunodeficient (NOD/SCID) mice and tumor diameters were monitored daily (a and d). Fifteen days after injection, the tumors were excised and weighed (b and e). Macroscopic images of excised tumors were shown in c and f. Scale bars = 10 mm (c and f). Data are represented as the mean ± s.d. of minimum n = 6. Tumor volume and weight were calculated using Dunnett’s test and compared to parental cells.
