Table 3 Progression-free survival Cox regression analysis c-scores for subset of 166 non-squamous carcinoma patients with available mutation status of KRAS and STK11 genes.

From: Development of a prognostic multiomic biomarker of progression-free survival in advanced non-small cell lung cancer patients treated with first line immunotherapy

Model

Components

Fivefold cross-validated c-score, 95% CI

Clinical model

BMI, smoking status

0.56, [0.51, 0.59]

Combination model

Radiomic phenotypes, radiological variables (SUVmax, longest tumor diameter at baseline), pathological variable (PD-L1 expression, KRAS expression, STK11 expression)

0.6, [0.52, 0.61]

Combination clinical model

Radiomic phenotypes, radiological variables (SUVmax, longest tumor diameter at baseline), pathological variable (PD-L1 expression, KRAS expression, STK11 expression), BMI, smoking status

0.64, [0.57,0.68]

Multiomic graph phenotypes

Multiomic graph phenotypes

0.62, [0.58, 0.67]

Multiomic graph clinical model

Multiomic graph phenotypes, BMI, smoking status

0.68, [0.58, 0.69]