Table 10 Toxicity properties of oleocanthal, oleacein, luteolin, tyrosol, ezetimibe, and bempedoic acid.

From: Chemical evaluation of arbequina extra virgin olive oil with in silico analysis of its key phenolic compounds targeting LDL metabolism

Toxicity properties

Oleocanthal

Oleacein

Luteolin

Tyrosol

Ezetimibe

Bempedoic acid

hERG Blockers

0.073

0.049

0.069

0.152

0.624

0.013

DILI

0.089

0.209

0.796

0.039

0.187

0.104

AMES Mutagenicity

0.304

0.39

0.65

0.317

0.415

0.03

Rat Oral Acute toxicity

0.147

0.177

0.51

0.086

0.67

0.032

FDAMDD

0. 624

0.656

0.88

0.062

0.901

0.128

Carcinogenicity

0.359

0.118

0.689

0.456

0.646

0.115

Hematotoxicity

0.136

0.099

0.029

0.116

0.577

0.272

Genotoxicity

0.927

0.962

0.986

0.019

0.998

0.003

RPMI-8226 Immunitoxicity

0.045

0.024

0.025

0.042

0.029

0.036

A549 Cytotoxicity

0.026

0.147

0.096

0.477

0.619

0.003

Hek293 Cytotoxicity

0.205

0.107

0.242

0.473

0.942

0.003

Drug-induce d Neurotoxicity

0.729

0.255

0.212

0.204

0.969

0.006

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