Table 11 Biological targets of oleocanthal, oleacein, luteolin, tyrosol, ezetimibe, and bempedoic acid.

From: Chemical evaluation of arbequina extra virgin olive oil with in silico analysis of its key phenolic compounds targeting LDL metabolism

Biological target

Oleocanthal

Oleacein

Luteolin

Tyrosol

Ezetimibe

Bempedoic acid

Sars-Cov

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y.reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y.reliable

E. coli

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N.1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:0.6

M:0.4

N.0.6

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

C. albicans

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

K: Active

L:0.8

M:0.8

N:0.2

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Active

L:0.8

M:0.8

N:0.2

Y: reliable

K: Inactive

L:1.0

M:0.0

N.1.0

Y: reliable

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

Dengue larvicida

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

K: Active

L:0.8

M:0.8

N:0.2

Y: reliable

K: Inactive

L:0.6

M:0.4

N.0.6

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

Salmonella

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: unreliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y.reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

Hepatite C - Type1

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y.reliable

K: Inactive

L:1.0

M:0.0

N.1.0

Y.reliable

Leishmania infantum - Promastigota

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

Leishmania amazonensis - Promastigota

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Inactive

L:0.6

M:0.4

N.0.6

Y: reliable

Drosophila melanogaster

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

K.Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y.reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

Leishmania braziliensis

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K.Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

K: Inactive

L:0.8

M.0.2

N:0.8

Y: reliable

K: Active

L:1.0

M:1.0

N:0.0

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

Leishmania major

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

K.Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K.Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:0.8

M:0.2

N:0.8

Y: reliable

Epimastigote Chagas

K: Active

L:0.8

M:0.8

N:0.2

Y: reliable

K: Active

L:0.6

M:0.6

N:0.4

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M.0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

K: Inactive

L:1.0

M:0.0

N:1.0

Y: reliable

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