Table 7 Distribution properties of oleocanthal, oleacein, luteolin, tyrosol, ezetimibe, and bempedoic acid.

From: Chemical evaluation of arbequina extra virgin olive oil with in silico analysis of its key phenolic compounds targeting LDL metabolism

Distribution properties

Oleocanthal

Oleacein

Luteolin

Tyrosol

Ezetimibe

Bempedoic acid

PPB

90.175

71.226

97.642

34.6

90.458

77.687

VDss

0.113

-0.223

-0.614

0.454

0.082

-0.326

BBB

0.0

0.0

0.012

0.189

0.002

0.0

Fu

11.572

26.918

2.286

59.526

9.367

16.981

OATP1B1 inhibitor

0.944

0.925

0.871

0.922

0.096

0.506

OATP1B3 inhibitor

0.805

0.84

0.984

0.882

0.076

0.106

BCRP inhibitor

0.372

0.552

0.955

0.493

0.002

0.008

MRP1 inhibitor

0.164

0.229

0.804

0.404

0.74

0.998

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