Table 1 Evaluation of genotoxic parameters in Allium Cepa root meristem cells exposed to increasing concentrations of ornidazole.

Mitotic index

(%)

897 ± 15.1^a

(8.97)

834 ± 16.1^b

(8.34)

793 ± 16.4^c

(7.93)

729 ± 13.9^d

(7.29)

675 ± 11.2^e

(6.75)

Micronucleus

0.20 ± 0.42^e

16.7 ± 1.77^d

37.7 ± 2.98^c

69.3 ± 4.40^b

75.7 ± 8.27^a

Sticky chromosome

0.40 ± 0.52^e

15.9 ± 3.00^d

35.0 ± 3.46^c

65.7 ± 3.59^b

72.7 ± 4.74^a

Binuclear cell

0.00 ± 0.00^e

13.6 ± 3.89^d

30.4 ± 3.78^c

61.4 ± 3.72^b

71.9 ± 3.95^a

Vagrant chromosome

0.30 ± 0.48^e

11.0 ± 2.75^d

25.5 ± 3.10^c

53.7 ± 3.23^b

67.7 ± 3.82^a

Disorientation

0.00 ± 0.00^e

10.9 ± 2.28^d

24.5 ± 2.55^c

50.7 ± 3.56^b

56.4 ± 4.16^a

Unequal distribution of chromatin

0.00 ± 0.00^e

10.0 ± 2.36^d

21.7 ± 2.95^c

43.7 ± 3.40^b

51.5 ± 3.72^a

Bridge

0.00 ± 0.00^e

9.20 ± 2.49^d

19.4 ± 3.24^c

40.7 ± 3.62^b

48.3 ± 4.20^a

Nucleus bud

0.00 ± 0.00^e

8.40 ± 2.37^d

16.3 ± 2.31^c

35.0 ± 2.79^b

41.0 ± 3.81^a

Fragment

0.00 ± 0.00^e

5.80 ± 1.69^d

14.0 ± 2.54^c

29.2 ± 3.08^b

34.9 ± 3.59^a