Fig. 1 | Scientific Reports

Fig. 1

From: LncRNA HOXA11-AS promotes the cell proliferation, migration, invasion and inhibits cell apoptosis in esophageal squamous cell carcinoma

Fig. 1

The clinical value of screening HOXA11-AS and the construction of overexpression and knockdown models. (A) The volcano plot screened high and low expression lncRNA from 5 pairs of ESCC cancer tissues and para-cancer tissues; (B) 50 pairs of ESCC tissues and para-cancer tissues were collected to detect the relative expression level of HOXA11-AS; (C) expression levels of HOXA11-AS in ESCC cell lines (ECA109, KYSE150, TE-1, KYSE410, TE-3) and normal esophageal epithelial cell line (HET-1A); ROC curve visualized the diagnostic efficacy of HOXA11-AS in outcome, TNM, age, gender, tumor location, differentiation and lymph node metastasis(D); construction of overexpression models(E) and knockdown models(I) of ECA109, KYSE150 and TE-1 and verification of the relative expression level of HOXA11-AS(F–H, J–L). ns: not significant (P > 0.05); *:P < 0.05; ***: P < 0.001; ****: P < 0.0001.

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