Fig. 1

Low expression of UBE2S in colorectal cancer enhances its proliferation. (A) High expression of UBE2S is positively correlated with overall survival rate in CRC patients; (B) UBE2S protein expression is lower in CRC tissues than in adjacent tissues (n = 6, 400×); (C) and (D) qPCR and protein analysis of stable cell line HCT116 and RKO with UBE2S knockdown or overexpression; (E) CCK8 experiments on HCT116 and RKO cell lines (n = 3); (F) Colony formation assays on HCT116 and RKO cell lines (n = 3); (G) Flow cytometry experiments are conducted on HCT116 and RKO cell lines (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ‘ns’ represents no statistical significance.