Fig. 6
From: Investigating the effects of miR-526b and miR-655 on doxorubicin sensitivity in breast cancer
Cell line comparison of DOX response and identification of network hub genes. Venn diagrams comparing (A) upregulated and (B) downregulated DEGs between each cell line after DOX treatment. Dot plots depicting the top ten enriched biological processes associated with the (C) 473 common upregulated DEGs and (D) 324 common downregulated DEGs. Interaction networks of (E) upregulated and (F) downregulated DEGs. (G) The top 5 hub genes from each network. Heat maps display the expression of each identified hub gene in each experimental cell line relative to MCF7 in (H) control (DMSO) and (I) DOX treatment conditions.
