Table 6 Determinants of clinically significant potential drug-drug interactions at bivariate and multivariable levels in asmara, eritrea, 2023.
Variable | Category | Bivariate analysis | Multivariable analysis | ||
|---|---|---|---|---|---|
COR (95% CI) | P-value | AOR (95%CI) | P-value | ||
Age, in years | 0 to 17 | Ref. | - | Ref. | - |
18 to 64 | 5.29 (1.99, 14.05) | 0.001 | 4.23 (1.49, 12.01) | 0.007 | |
65 and above | 10.31 (3.55, 29.95) | < 0.001 | 7.09 (2.24, 22.44) | 0.001 | |
Sex | Male | 0.87 (0.50, 1.50) | 0.619 | - | - |
Female | Ref. | - | - | - | |
Prescriber qualification | Specialist | Ref. | - | - | - |
GP | 0.71 (0.24, 2.10) | 0.531 | - | - | |
GP intern | 0.30 (0.03, 3.25) | 0.322 | - | - | |
Nurse | 0.49 (0.16, 1.51) | 0.213 | - | - | |
Number of drugs prescribed | - | 2.60 (1.81, 3.75) | < 0.001 | 2.27 (1.53, 3.37) | < 0.001 |
Level of health facility | Primary | Ref. | - | Ref. | - |
Secondary | 6.05 (0.72, 50.93) | 0.098 | 2.60 (0.29, 23.61) | 0.397 | |
Tertiary | 18.28 (2.44, 136.91) | 0.005 | 9.13 (1.17, 71.42) | 0.035 | |
