Table 2 The unadjusted association between baseline variables and 30-day mortality (n = 16,691) Abbrevations: GCS, Glasgow Coma Scale; SOFA, Sequential Organ Failure Assessment; APACHE IV, Acute Physiology and Chronic Health Evaluation IV; MELD-XI, Model for End-Stage Liver Disease Excluding INR.
Expoure | Statistics | Odds ratio (95% CI) | P-value |
---|---|---|---|
MELD-XI | 17.69 ± 7.16 | 1.04 (1.04, 1.05) | < 0.0001 |
MELD-XI tertile | |||
Low | 5520 (33.07%) | 1.0 | |
Middle | 5586 (33.47%) | 1.57 (1.41, 1.75) | < 0.0001 |
High | 5585 (33.46%) | 1.99 (1.79, 2.21) | < 0.0001 |
Ethnicity | |||
African American | 1770 (10.69%) | 1.0 | |
Asian | 284 (1.71%) | 1.43 (1.04, 1.96) | 0.0261 |
Caucasian | 12,829 (77.47%) | 1.09 (0.95, 1.25) | 0.2414 |
Hispanic | 728 (4.40%) | 1.08 (0.85, 1.37) | 0.5257 |
Native American | 134 (0.81%) | 1.28 (0.81, 2.01) | 0.2864 |
Other/Unknown | 815 (4.92%) | 0.90 (0.71, 1.14) | 0.3752 |
Gender | |||
Female | 7859 (47.09%) | 1.0 | |
Male | 8829 (52.91%) | 1.07 (0.98, 1.16) | 0.1152 |
Age | 65.0 ± 15.96 | 1.02 (1.02, 1.02) | < 0.0001 |
Total Bilirubin | 1.71 ± 2.63 | 1.08 (1.06, 1.09) | < 0.0001 |
Creatinine | 1.97 ± 1.08 | 1.21 (1.17, 1.26) | < 0.0001 |
Lactate | 3.33 ± 3.08 | 1.15 (1.13, 1.16) | < 0.0001 |
Pulmonary Infection | 6967 (41.74%) | 1.18 (1.09, 1.28) | < 0.0001 |
Renal/urinary tract infection | 1676 (10.04%) | 0.88 (0.76, 1.01) | 0.0685 |
Skin/Bone/joint Infection | 1129 (6.76%) | 0.74 (0.62, 0.89) | 0.0012 |
Gastrointestinal/Intra-abdominal Infection | 1043 (6.25%) | 1.12 (0.95, 1.33) | 0.1650 |
Septic shock | 7368 (44.14%) | 1.30 (1.19, 1.41) | < 0.0001 |
APACHE IV | 73.12 ± 27.32 | 1.03 (1.02, 1.03) | < 0.00001 |
SOFA | 8.06 ± 3.59 | 1.24 (1.23, 1.26) | < 0.00001 |
GCS | 9.59 ± 4.37 | 0.81 (0.80, 0.82) | < 0.00001 |
Congestive heart failure | 3165 (18.96%) | 1.09 (0.98, 1.21) | 0.0949 |
Cardiac arrhythmias | 3405 (20.40%) | 1.42 (1.29, 1.57) | < 0.0001 |
Severe liver disease | 462 (2.77%) | 2.12 (1.72, 2.60) | < 0.0001 |
Renal failure | 2540 (15.22%) | 1.21 (1.08, 1.35) | 0.0007 |
Malignant cancer | 2483 (14.88%) | 1.59 (1.43, 1.77) | < 0.0001 |
Metastatic solid tumor | 512 (3.07%) | 2.57 (2.13, 3.11) | < 0.0001 |
History of dialysis | 964 (5.78%) | 0.71 (0.58, 0.86) | 0.0006 |