Table 3 Clinical outcomes of patients with acute myocardial infarction according to Statin treatment at discharge during 3-year follow-up.

From: High-intensity statin on 3-year clinical outcomes in elderly acute myocardial infarction patients underwent percutaneous coronary intervention with drug-eluting stents

Clinical outcomes

High-statin

(n = 521)

Low/Moderate-statin

(n = 1419)

No statin

(n = 123)

P-value

Primary endpoint

Cardiac death or MI

60 (11.5)

177 (12.5)

27 (22.0)

0.001

Secondary endpoint

    

MACE*

106 (20.3)

311 (21.9)

44 (35.8)

0.001

TLF**

50 (9.6)

165 (11.6)

27 (22.0)

0.001

TVF***

70 (13.4)

207 (14.6)

32 (26.0)

0.002

PFCE****

104 (20.0)

341 (24.0)

49 (39.8)

< 0.001

Total death

70 (13.4)

217 (15.2)

35 (28.4)

< 0.001

Cardiac death

42 (8.0)

134 (9.4)

24 (19.5)

< 0.001

Non-cardiac death

28 (5.3)

83 (5.8)

11 (8.9)

0.315

Myocardial infarction

23 (4.4)

52 (3.6)

5 (4.0)

0.745

STEMI

6 (1.1)

9 (0.6)

1 (0.8)

0.515

NSTEMI

17 (3.2)

43 (3.0)

4 (3.2)

0.962

Repeat revascularization

40 (7.6)

94 (6.6)

9 (7.3)

0.710

TLR

8 (1.5)

32 (2.2)

3 (2.4)

0.592

TVR

18 (3.4)

52 (3.6)

5 (4.0)

0.943

Non-TVR

23 (4.4)

45 (3.1)

5 (4.0)

0.400

Stroke

14 (2.6)

46 (3.2)

4 (3.2)

0.819

Hemorrhagic

2 (0.4)

12 (0.8)

1 (0.8)

0.566

Ischemic

9 (1.7)

34 (2.4)

3 (2.4)

0.668

Stent thrombosis

4 (0.7)

6 (0.4)

0 (0.0)

0.455

Re-hospitalization

27 (5.1)

113 (7.9)

16 (13.0)

0.008

  1. Data are presented as N (%). MI, myocardial infarction; MACE, major adverse cardiac events; TLF, target lesion failure; TVF, target vessel failure; PFCE, procedure free cardiac events; STEMI, ST-segment elevation myocardial infarction; NSTEMI, non-ST-segment elevation myocardial infarction; TLR, target lesion revascularization; TVR, target vessel revascularization.
  2. †P-values were calculated using the chi-square test or Fisher’s exact test, as appropriate.
  3. *MACE was defined as a composite of total death, MI, and repeat revascularization.
  4. **TLF was defined as a composite of cardiac death, STEMI, and TLR.
  5. ***TVF was defined as a composite of cardiac death, MI, and TVR.
  6. ****PFCE was defined as a composite of cardiac death, MI, and re-hospitalization.