Table 2 Cox regression analysis of LAR and 28d, 90d, 180d mortality in liver cirrhosis patients.

From: Lactate to albumin ratio as a novel predictor of short-term prognosis for liver cirrhosis in ICU

Factor

Model1

Model2

Model3

HR

95% CI

P

HR

96% CI

P

HR

97% CI

P

28-day mortality

P for trend:<0.001

P for trend:<0.001

P for trend: <0.001

Q1

–

–

 

–

–

 

–

–

 

Q2

1.476

1.123, 1.938

0.005

1.467

1.116, 1.928

0.006

1.275

0.964, 1.687

0.088

Q3

2.239

1.734, 2.890

<0.001

2.255

1.745, 2.913

<0.001

1.532

1.169, 2.009

0.002

Q4

3.653

2.869, 4.651

<0.001

3.693

2.893, 4.714

<0.001

2.078

1.580, 2.733

<0.001

90-day mortality

P for trend:<0.001

P for trend:<0.001

P for trend:<0.001

Q1

–

–

 

–

–

 

–

–

 

Q2

1.43

1.138, 1.797

0.002

1.423

1.133, 1.789

0.002

1.251

0.990, 1.582

0.061

Q3

2.102

1.695, 2.607

<0.001

2.127

1.714, 2.640

<0.001

1.498

1.190, 1.884

<0.001

Q4

3.094

2.517, 3.803

<0.001

3.184

2.585, 3.923

<0.001

1.895

1.496, 2.400

<0.001

180-day mortality

P for trend<0.001

P for trend:<0.001

P for trend:<0.001

Q1

–

–

 

–

–

 

–

–

 

Q2

1.338

1.084, 1.652

0.007

1.332

1.079, 1.645

0.008

1.184

0.954, 1.471

0.125

Q3

1.96

1.607, 2.391

<0.001

1.985

1.626, 2.423

<0.001

1.433

1.159, 1.772

<0.001

Q4

2.757

2.277, 3.339

<0.001

2.854

2.352, 3.464

<0.001

1.773

1.423, 2.209

<0.001

365-day mortality

P for trend:<0.001

P for trend:<0.001

P for trend:<0.001

Q1

–

–

 

–

–

 

–

–

 

Q2

1.223

1.007, 1.485

0.042

1.219

1.004, 1.481

0.045

1.088

0.891, 1.328

0.407

Q3

1.843

1.536, 2.210

<0.001

1.87

1.558, 2.245

<0.001

1.386

1.140, 1.684

0.001

Q4

2.482

2.081, 2.960

<0.001

2.588

2.166, 3.093

<0.001

1.694

1.382, 2.075

<0.001

  1. HR, hazard ratio; CI, confidence interval.
  2. LAR index: Q1 (0.012–0.043), Q2 (0.043–0.064), Q3 (0.064–0.100), Q4 (0.100-1.838).
  3. Model 1: unadjusted; Model 2: adjusted for admission age, gender, race; Model 3: Admission_age, Gender, Race, HR, RR, Alt, Anion_gap, Ast, Bun, Calcium, Creatinine, Plt, Glucose, Hemoglobin, INR, Potassium, RDW, Sodium, TB, WBC, Viral hepatitis, Acute and subacute hepatic failure, AKI, Alcoholic cirrhosis, Atrial fibrillation, Autoimmune liver disease, Chronic hepatic failure, CRRT, Diabetes, Esophageal varices blooding, Fibrates, Heart failure, Hepatic encephalopathy, Hypertension, nonalcoholic steatohepatitis, Obesity, Respiratory failure, Sepsis, Statins, Vasopressin, Mechanical ventilation.
Back to article page