Fig. 5

Oral fungal microbial diversity between PIOV group and PIOS group. (A,B) The results of ace and chao showed that the α-diversity of oral fungal microorganisms in PIOV group was significantly lower than PIOS group. (C) Venn diagram showing overlap between groups shows that the PIOV and PIOS groups have a total of 3,532 OTUs, the PIOV group has 30,453 OTUs, and the PIOS group has 9,736 OTUs. (D,E) PCoA and NMDS based on OTU distribution showed that there were significant differences in the classification composition of oral fungal microorganisms between the two groups, and the differences were statistically significant (F). PIOV, patients infected Omicron variant; PIOS, patients infected original strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); OTUs, operational taxonomy units; PCoA, principal coordinate analysis; NMDS, nonmetric multidimensional scaling; centerline, median; box limits, upper and lower quartiles; error bars, 95% CI.