Table 1 Clinical characteristics of subjects in discovery and validation cohorts.
From: Dynamic alterations of oral fungal microbiota in Omicron infected patients
Clinical indicators | Discovery cohort (n = 424) | p-value | Validation cohort (n = 211) | p-value | ||
|---|---|---|---|---|---|---|
HC (n = 200) | PIOV (n = 224) | HC (n = 99) | PIOV (n = 112) | |||
Age (years) | 28.6\(\:\pm\:\)9.64 | \(\:28.4\pm\:9.78\) | 0.882 | 30.4\(\:\pm\:\)10.7 | \(\:29.0\pm\:10.2\) | 0.336 |
Sex (female/male) | 95/105 | 99/125 | 0.559 | 45/54 | 46/66 | 0.615 |
Laboratory results | Â | Â | Â | Â | Â | Â |
White blood cells (109L−1) | 6.09\(\:\pm\:1.60\) | 5.03\(\:\pm\:1.48\) | \(\:<0.001\) | 6.01\(\:\pm\:1.65\) | 5.78\(\:\pm\:5.70\) | 0.679 |
Neutrophils (109L−1) | 3.52\(\:\pm\:1.34\) | 2.59\(\:\pm\:1.17\) | \(\:<0.001\) | 3.48\(\:\pm\:1.23\) | 2.72\(\:\pm\:1.17\) | \(\:<0.001\) |
Lymphocytes (109L−1) | 1.99\(\:\pm\:\)0.552 | 1.92\(\:\pm\:0.655\) | 0.203 | 1.98\(\:\pm\:\)0.603 | 2.01\(\:\pm\:0.619\) | 0.792 |
Blood Platelet (109L−1) | 248\(\:\pm\:\)59.0 | \(\:206\pm\:\)50.1 | \(\:<0.001\) | 241\(\:\pm\:\)56.5 | \(\:201\pm\:\)43.8 | \(\:<0.001\) |
Hemoglobin (gL− 1) | \(\:138\pm\:16.3\) | \(\:149\pm\:39.2\) | \(\:<0.001\) | \(\:140\pm\:13.2\) | \(\:146\pm\:19.1\) | \(\:0.011\) |
Alanine aminotransferase (UL− 1) | \(\:17.1\pm\:11.9\) | \(\:24.8\pm\:26.3\) | \(\:<0.001\) | \(\:18.5\pm\:12.9\) | \(\:22.9\pm\:27.4\) | 0.135 |
Aspartate aminotransferase (UL− 1) | \(\:19.3\pm\:9.94\) | \(\:21.3\pm\:11.8\) | 0.0609 | \(\:19.9\pm\:6.02\) | \(\:23.0\pm\:23.9\) | 0.178 |
Albumin (gL− 1) | \(\:46.6\pm\:3.55\) | \(\:43.5\pm\:3.91\) | \(\:<0.001\) | \(\:46.6\pm\:3.49\) | \(\:42.4\pm\:3.26\) | \(\:<0.001\) |
Total bilirubin (µmolL− 1) | \(\:9.01\pm\:\)4.63 | \(\:12.6\pm\:5.84\) | \(\:<0.001\) | \(\:9.23\pm\:\)4.68 | \(\:7.12\pm\:29.4\) | 0.338 |
Serum creatinine (µmolL− 1) | \(\:69.5\pm\:\)14.3 | \(\:71.4\pm\:\)13.0 | 0.145 | \(\:69.2\pm\:\)15.3 | \(\:72.6\pm\:\)12.6 | 0.082 |
