Table 1 Retrospective analysis demographic baseline characteristics.

From: Development and validation of the HIGHT prediction model for early hematoma expansion in spontaneous intracerebral hemorrhage

 

Overall

Non-EHE

EHE

P-Value

N

532

475

57

 

General information

 Age (mean ± SD)

59.51 (10.73)

59.69 (10.59)

58.02 (11.81)

0.267

 Gender(%)

1

  Male

337(63.3)

301(63.4)

36(63.2)

 

  Female

195 (36.7)

174 (36.6)

21 (36.8)

 

 HP = 1 (%)

346 (65.0)

308 (64.8)

38 (66.7)

0.9

 DM = 1 (%)

71 (13.3)

63 (13.3)

8 (14.0)

1

 Smoking(%)

68 (12.8)

59 (12.4)

9 (15.8)

0.61

 Taking

anticoagulants(%)

29 (5.5)

24 (5.1)

5 (8.8)

0.39

 Time-to-CT

4

[1.00, 21.00]

4

[1.00, 21.00]

3

[1.00, 6.00]

< 0.001

GCS (IQR)

11.00

[8.00, 13.00]

11.00

[8.00, 13.00]

9.00

[8.00, 11.00]

0.003

 T (IQR)

36.80

[36.50, 37.10]

36.80

[36.50, 37.10]

36.90

[36.50, 37.20]

0.369

 SBP (IQR)

156.00

[146.00, 168.00]

156.00

[146.00, 166.00]

165.00

[153.00, 184.00]

0.002

 DBP (IQR)

88.50

[79.00, 98.00]

88.00

[79.00, 97.00]

93.00

[85.00, 103.00]

0.015

Laboratory tests

 Glu (mean ± SD)

8.05 (2.99)

8.08 (3.00)

7.82 (2.88)

0.539

 K (mean ± SD)

3.50 (0.44)

3.51 (0.45)

3.48 (0.39)

0.616

 Na (mean ± SD)

137.52 (3.48)

137.40 (3.45)

138.51 (3.60)

0.022

 Ca (mean ± SD)

2.36 (0.16)

2.36 (0.16)

2.38 (0.16)

0.402

 P (mean ± SD)

0.87 (0.27)

0.87 (0.28)

0.87 (0.23)

0.934

 Albumin (mean ± SD)

40.75 (4.10)

40.76 (4.16)

40.69 (3.52)

0.907

 WBC (mean ± SD)

9.63 (3.73)

9.70 (3.66)

9.00 (4.20)

0.179

 Neutrophil

(mean ± SD)

7.88 (3.78)

7.96 (3.73)

7.24 (4.22)

0.178

 Lymphocyte

(mean ± SD)

1.16 (0.66)

1.15 (0.65)

1.24 (0.74)

0.341

 HB (mean ± SD)

150.95 (23.66)

150.99 (23.72)

150.54 (23.39)

0.892

 PLT (mean ± SD)

173.22 (64.20)

174.67 (63.55)

161.18 (68.79)

0.134

 PT (mean ± SD)

11.77 (2.43)

11.71 (2.23)

12.25 (3.66)

0.114

 INR (mean ± SD)

1.20 (3.56)

1.21 (3.77)

1.08 (0.34)

0.786

 APTT (mean ± SD)

25.48 (5.30)

25.39 (5.28)

26.21 (5.46)

0.266

 FIB (mean ± SD)

3.00 (1.48)

3.01 (1.52)

2.89 (1.00)

0.542

 TT (mean ± SD)

16.70 (3.87)

16.63 (4.04)

17.34 (1.96)

0.191

 D_dimer

(mean ± SD)

1.65 (5.68)

1.57 (5.24)

2.29 (8.54)

0.371

Imaging information

 Hemorrhage volume

(IQR)

15.48

[6.86, 28.32]

15.31

[6.20, 28.27]

17.90

[11.03, 30.14]

0.124

 Middle line

(mean ± SD)

1.47 (3.34)

1.41 (3.31)

1.89 (3.62)

0.305

 Hematoma into

ventricle(%)

148 (27.8)

132 (27.8)

16 (28.1)

1

Location (%)

0.268

 Basal ganglia

342 (64.3)

298 (62.7)

44 (77.2)

 

 Lobes

81 (15.2)

74 (15.6)

7 (12.3)

 

 Cerebellum

18 (3.4)

17 (3.6)

1 (1.8)

 

 Brainstem

19 (3.6)

19 (4.0)

0 (0.0)

 

 Ventricle

28 (5.3)

27 (5.7)

1 (1.8)

 

 Thalamus

44 (8.3)

40 (8.4)

4 (7.0)

 

 Fluid level(%)

11 (2.1)

10 (2.1)

1 (1.8)

1

 Island sign(%)

24 (4.5)

17 (3.6)

7 (12.3)

0.008

 Black hole sign(%)

3 (0.6)

2 (0.4)

1 (1.8)

0.738

 Hypodensity(%)

29 (5.5)

18 (3.8)

11 (19.3)

< 0.001

  1. HP: hypertension, DM: diabetes mellitus, T: temperature, SBP: systolic blood pressure, DBP: diastolic blood pressure, Glu: glucose, WBC: white blood cell, HB: hemoglobin, PLT: platelet, PT: prothrombin time, INR: International normalized ratio, APTT: activated partial thromboplastin time, FIB: fibrinogen, TT: thromboplastin time. Time-to-CT: Time from Symptom Onset to CT.
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