Table 2 Baseline characteristics of the combined training and internal validation cohort stratified by DILI status.
Variables | Total N = 2160 (%) | DILI N = 108 (%) | Non-DILI N = 2052 (%) | P |
|---|---|---|---|---|
Gender | 0.740 | |||
Female | 752 (34.8) | 36 (33.3) | 716 (34.9) | |
Male | 1408 (65.2) | 72 (66.7) | 1336 (65.1) | |
Age (yrs) | < 0.001 | |||
< 60 | 929 (43.0) | 28 (25.9) | 901 (43.9) | |
≥ 60 | 1231 (57.0) | 80 (74.1) | 1151 (56.1) | |
BMI (kg/m2) | 0.011 | |||
< 18.5 | 627 (29.0) | 43 (39.8) | 584 (28.5) | |
≥ 18.5 | 1533 (71.0) | 65 (60.2) | 1468 (71.5) | |
Smoking | 0.950 | |||
No | 1454 (67.3) | 73 (67.6) | 1381 (67.3) | |
Yes | 706 (32.7) | 35 (32.4) | 671 (32.7) | |
Drinking | < 0.001 | |||
No | 1557 (72.1) | 60 (55.6) | 1497 (73.0) | |
Yes | 603 (27.9) | 48 (44.4) | 555 (27.0) | |
Diabetes | 0.424 | |||
No | 1930 (89.4) | 94 (87.0) | 1836 (89.5) | |
Yes | 230 (10.6) | 14 (13.0) | 216 (10.5) | |
Hypertension | 0.405 | |||
No | 1575 (72.9) | 75 (69.4) | 1500 (73.1) | |
Yes | 585 (27.1) | 33 (30.6) | 552 (26.9) | |
Extrapulmonary TB | 0.001 | |||
No | 1482 (68.6) | 58 (53.7) | 1424 (69.4) | |
Yes | 678 (31.4) | 50 (46.3) | 628 (30.6) | |
Albumin (g/L) | < 0.001 | |||
< 35 | 490 (22.7) | 45 (41.7) | 445 (21.9) | |
≥ 35 | 1670 (77.3) | 63 (58.3) | 1607 (78.1) | |
WBC (× 109/L) | 6.33 ± 2.61 | 6.23 ± 2.58 | 6.36 ± 2.52 | 0.602 |
RBC (109/L) | 4.28 ± 2.41 | 4.21 ± 2.32 | 4.31 ± 2.28 | 0.657 |
HB (g/L) | 0.003 | |||
< 110 | 468 (21.7) | 36 (33.3) | 432 (21.1) | |
≥ 110 | 1692 (78.3) | 72 (66.7) | 1620 (78.9) | |
NEU (109/L) | 4.83 ± 2.55 | 5.19 ± 2.96 | 4.80 ± 2.48 | 0.115 |
PLT (109/L) | 225.12 ± 48.43 | 231.11 ± 52.14 | 223.20 ± 49.43 | 0.106 |
