Fig. 8 | Scientific Reports

Fig. 8

From: Protective potential of tween 80-functionalized chitosan-selenium nanoparticles containing quercetin against cisplatin neurotoxicity in PC12 cells: an in vitro and network pharmacology study

Fig. 8

Cell viability of PC12 cells pre-exposed to Q-Tw-Cs@Se NPs and quercetin for 24 h before addition of cisplatin (80 µg/mL). Each value is represented as mean ± SD, n = 3. A two-way ANOVA was used for statistical comparison among groups, followed by Tukey’s post-test, and statistical significance compared to the model group (untreated + cisplatin) is denoted as follows: *P < 0.05, &P < 0.01, $P < 0.001, and #P < 0.0001. Statistical significance between two groups at the same concentration is indicated as follows: ^P < 0.05, ^^P < 0.01, ^^^P < 0.001, and ^^^^P < 0.0001.

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