Table 2 Mean ΔCt values (± SD) for SSNHL patients and controls, ΔΔCt, fold change (2^−ΔΔCt), and statistical significance for each miRNA.

From: Differential expression of miR-23a-3p/-210-3p and /-18b-5p in sudden sensorineural hearing loss patients: A North American cohort study

miRNA

ΔCt SSNHL

[Mean ± SD or Median (IQR)]

ΔCt Control

[Mean ± SD or Median (IQR)]

ΔΔCt

(SSNHL–Control)

Fold Change (2^-ΔΔCt)

p-value

miR-15a-5p

-0.578 ± 3.498

0.033 ± 0.541

-0.611

1.53

0.05

miR-18b-5p

3.00 (2.40)

4.20 (1.03)

-1.291

2.45

0.02*

miR-210-3p

4.620 ± 2.337

7.371 ± 1.762

-2.751

6.73

0.006**

miR-143-3p

1.162 ± 7.136

2.512 ± 0.687

-1.350

2.55

0.36

miR-183-5p

4.084 ± 6.647

5.586 ± 1.219

-1.502

2.83

0.34

miR-23a-3p

-2.84 (2.22)

1.62 (0.64)

-3.443

10.87

0.001***

  1. Values are presented as mean ± standard deviation for normally distributed data and as median (IQR) for non-parametric data. ΔΔCt values represent the difference between SSNHL and controls. Fold change was calculated as 2^-ΔΔCt. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***).
Back to article page