Table 5 Chemical and physical properties of drugs.

From: Applications of Sombor topological indices and entropy measures for QSPR modeling of anticancer drugs: a Python-based methodology

Drugs

BP (\(^\circ \hbox {C}\))

MR (\(\hbox {cm}^3\))

HAC

EM (Da)

FP (\(^\circ \hbox {C}\))

P (\(\hbox {cm}^3\))

Afatinib

676.9

131.2

34

485.16

363.2

52

Alpelisib

 

106.7

30

441.14

 

42.3

Anastrozole

469.7

90

22

293.16

237.9

35.7

Belinostat

 

83

22

318.06

 

32.9

Bortezomib

 

103

28

384.19

 

40.8

Busulfan

464

50.9

14

246.02

234.4

20.2

Carmustine

309.6

46.6

12

213

141

18.5

Dasatinib

 

132

33

487.15

 

52.3

Daunorubicin

770

130

38

527.17

419.5

51.5

Erdafitinib

662.3

129.6

33

446.24

354.4

51.4

Flutamide

400.3

61.3

19

276.07

195.9

24.3

Futibatinib

733.8

115.8

31

418.17

397.6

45.9

Granisetron

532

89.8

23

312.19

275.6

35.6

Ibrutinib

715

126.1

33

440.19

386.2

50

Lenalidomide

614

66.5

19

259.09

325.1

26.3

Lomustine

 

57.8

15

233.09

 

22.9

Melphalan

473.1

78.8

19

304.07

239.9

31.2

Midostaurin

 

160.3

43

570.22

 

63.5

Mitomycin C

581.8

80.8

24

334.12

305.6

32

Nilotinib

 

141.8

39

529.18

 

56.2

Olaparib

 

116.9

32

434.17

 

46.3

Olutasidenib

603.3

93.4

25

354.08

318.7

37

Orgovyx

 

158.2

44

623.17

 

62.7

Plerixafor

657.5

151.5

36

502.44

361.8

60.1

Pomalidomide

582.9

66.6

20

273.07

306.3

26.4

Pralatrexate

 

125.9

35

477.17

 

49.9

Prednisone

573.7

94.1

26

358.17

314.8

37.3

Repotrectinib

 

93.2

26

355.14

 

37

Ribociclib

730.8

123.4

32

434.25

395.8

48.9

Zanubrutinib

713.4

133.1

35

471.22

385.2

52.8